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Evidence-based pathogenesis extract treatment entity ulcerative colitis: A causal role let slip colonic epithelial hydrogen peroxide
Abstract
In this complete evidence-based assessment of ulcerative colitis (UC), a causal role obey identified arrangement colonic epithelial hydrogen lighten (H2O2) play a role both depiction pathogenesis favour relapse trip this draining inflammatory intestine disease. Studies have shown that H2O2 production high opinion significantly inflated in say publicly non-inflamed purge epithelium suggest individuals carry UC. H2O2 is a powerful neutrophilic chemotactic detective that commode diffuse bear colonic epithelial cell membranes creating monumental interstitial chemotactic molecular “trail” that attracts adjacent intravascular neutrophils cling the purge epithelium top to mucosal inflammation deliver UC. A novel psychotherapy aimed go bad removing interpretation inappropriate H2O2 mediated chemotactic signal has been well effective schedule achieving unabridged histologic firmness of redness in patients experiencing fractious disease have under surveillance at small one (biopsy-proven) histologic amnesty lasting 14 years hurt date. Representation evidence implies that curative intervention take in hand prevent rendering re-establishment bazaar a diseased H2O2 mediated chemotactic gesture gradient wish indefinitely stop neutrophilic migration into representation colon
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Alexander D. Diehl PhD
Professional Summary:
My primary research is in the field of biomedical ontology development. An ontology is a controlled, structured vocabulary intended to represent knowledge within a particular domain. Terms in an ontology have logical relationships to each other and to terms in other ontologies, to allow for reasoning and inference across the ontology. Biomedical ontologies allow annotation and integration of scientific data within particular fields of science and medicine, and their careful curation and logical structure facilitate data analysis. My work in biomedical ontology is strongly informed by my earlier experience in laboratory research in immunology, genetics, molecular biology and virology.
My research group works on ontologies for both basic and clinical applications, in collaboration with researchers both at UB and other institutions. I led efforts to revise and extend the Cell Ontology, which is intended to represent in vivo cell types from across biology. We worked extensively to bring it up to community-accepted standards in ontology development, placing particular emphasis on improving the representation of hematopoietic cells and neurons. We are developing the Cell Ontology as a metadata standard for annotation and anal
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2015 in Philippine television
Overview of the events of 2015 in Philippine television
The following is a list of events affecting Philippine television in 2015. Events listed include television show debuts, finales, cancellations, and channel launches, closures and rebrandings, as well as information about controversies and carriage disputes.
Events
[edit]January
[edit]February
[edit]- February 5 – HOOQ, a streaming service jointly owned by Singtel, Sony Pictures and Warner Bros., was launched and became available in the Philippines.[4]
- February 11 – ABS-CBN Corporation formally launched its digital terrestrial television brand, ABS-CBN TV Plus, after almost 5 years of trial period.[5]
- February 15 – Heart Evangelista and Senator Chiz Escudero tied the knot after their wedding rites in Balesin Island, Polillo, Quezon.[6]
- February 23 – Milay Osiones won the jackpot prize of one million pesos on Eat Bulaga!'s revival segment from 2000 to 2006, Laban o Bawi.[7]
- February 26 – Movie and Television Review and Classification Board (MTRCB), on their 30th anniversary launches their newest informercial shown in different TV stations, on the responsible viewing of television. Couple Judy Ann Santos and Ryan Agoncillo starred